Waggoner Lab on X: "Cryopyrin-associated periodic syndrome (CAPS) NLRP3 variants form constitutively active inflammasomes inducing pyroptosis & IL-18 release without cell priming, contributing to autoinflammatory flares while metabolically limiting IL ...
Investigating the Role of NLRP3 Inflammasome and Immunometabolism in CAPS Patients - Medriva
PKD-mediated NLRP3 activation pathway and the relevant CAPS mutations.... | Download Scientific Diagram
Pathogenic NLRP3 mutants form constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1β production | Nature Communications
Pathophysiology of CAPS. Activation of the NLRP3 inflam | Open-i
INFLAMMASOME INHIBITORS - 21st Century Miracle Drugs: Spotlight on Clinical NLRP3 Inflammasome Inhibitors
IJMS | Free Full-Text | The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation
Frontiers | Regulation of NLRP3 Inflammasome by Phosphorylation
JCI - Confounding role of tumor necrosis factor in cryopyrin-associated periodic syndromes
Clinical manifestations of NLRP3 spectrum disease. CAPS,... | Download Scientific Diagram
NLRP3 Phosphorylation Is an Essential Priming Event for Inflammasome Activation - ScienceDirect
IJMS | Free Full-Text | The NLRP3 Inflammasome: Relevance in Solid Organ Transplantation
www.frontiersin.org/files/Articles/618231/fimmu-11...
Frontiers | Pharmacological Inhibitors of the NLRP3 Inflammasome
Cryo-sensitive aggregation triggers NLRP3 inflammasome assembly in cryopyrin-associated periodic syndrome | bioRxiv
PKA-mediated NLRP3 inhibition pathway and the relevant CAPS mutations.... | Download Scientific Diagram
Cells | Free Full-Text | Specific NLRP3 Inflammasome Assembling and Regulation in Neutrophils: Relevance in Inflammatory and Infectious Diseases
Nlrp3 inflammasome activation in macrophages suffices for inducing autoinflammation in mice | EMBO reports
Frontiers | The NLRP3 Inflammasome Pathway: A Review of Mechanisms and Inhibitors for the Treatment of Inflammatory Diseases
NLRP3 CAPS mutations and model of NEK7-mediated NLRP3 inflammasome... | Download Scientific Diagram
Targeting the NLRP3 inflammasome in inflammatory diseases | Nature Reviews Drug Discovery
Spotlight on the NLRP3 inflammasome pathway | JIR
Spotlight on the NLRP3 inflammasome pathway | JIR
NLRP3-associated autoinflammatory diseases: Phenotypic and molecular characteristics of germline versus somatic mutations - ScienceDirect
NLRP3 - Ventus Therapeutics
